Academic studies & publications

Academic publications utilizing disease-specific register data

The collected real-world data from BCB Medical’s Treatment Monitoring Systems can be utilised in various ways, for example in medical research and in the publication of scientific articles.

Here you can find a list of publications that have applied data collection methods that meet scientific research criteria and are ethically sustainable, utilising patient-specific data contained and produced by BCB Medical’s Treatment Monitoring System.

Aho, I., Kivelä, P., Kaijomaa, M., Surcel, H-M., Ristola, M., Heikinheimo, O., Sutinen,, J. with the FINHIVPREG Study Team (2018). Comprehensive nationwide analysis of mother-to-child HIV transmission in Finland from 1983 to 2013. Epidemiology and Infection, 146 (10). [Cited 2022-08-24].

Aho, I., Kaijomaa, Kivelä, P., M.,Surcel, H-M., Sutinen, J., Heikinheimo, O. with the FINHIVPREG Study team. (2018). Most women living with HIV can deliver vaginally – National data from Finland 1993-2013. PLoS One, 13 (3). [Cited 2022-08-25] .

Aho, I., Kivelä, P., Haukka, J., Sutinen, J., & Heikinheimo, O. (2017). Declining prevalence of cytological squamous intraepithelial lesions of the cervix among women living with wellcontrolled HIV – Most women living with HIV do not need annual PAP smear screening. Acta Obstet Gynecol Scand, 96 (11). [Cited 2022-08-25].

Ala-Seppälä, H., Heino, I., Frantzén, J., Takala, R.S.K., Katila, A.J., Kyllönen, A., Maanpää, H-R., Posti, JP., Tallus, J., & Tenovuo, O. (2016). Injury profiles, demography and representativeness of patients with TBI attending a regional emergency department. Brain Injury, 30 (9). [Cited 2022-08-25].

Eriksson, I.M., Gordin, D., Shams, S., Forsblom, Summanen, P., C., Liebkind, R., Tatlisumak, T., Putaala, J., Groop, P-H., Martola, J., & Thorn, L.M., on behalf of the FinnDiane Study Group (2020). Nocturnal Blood Pressure Is Associated With Cerebral Small-Vessel Disease in Type 1 Diabetes. Behalf of the FinnDiane Study Group. Diabetes care, 43 (8). [Cited 2022-08-25]

Gensicke, H., Al Sultan, AS., Strbian, D., Hametner, C., Zinkstok, SM., Moulin, S., Bill, O., Zini, A., Padjen, V., Kägi, G., Pezzini, A., Seiffge, DJ., Traenka, C., Räty, S., Amiri, H., Zonneveld, TP., Lachenmeier, R., Polymeris, A., Roos, YB., Gumbinger, C., Jovanovic, DR., Curtze, S., Sibolt, G., Vandelli, L., Ringleb, PA., Leys, D., Cordonnier, C., Michel, P., Lyrer, PA., Peters, N., Tatlisumak, T., Nederkoorn, PJ., & Engelter ST. (2018). Thrombolysis in Stroke Patients (TRISP) Collaborators. Intravenous thrombolysis and platelet count. Neurology, 90 (8). [Cited 2022-08-25].

Gensicke, H., Frih, AA., Strbian, D., Zini, A., Pezzini, A., Padjen, V., Haueter, M., Seiffge, DJ., Mäkitie, L., Traenka, C., Poli, L., Martinez-Majander, N., Putaala, J., Bonati, LH., Sibolt, G., Giovannini, G., Curtze, S., Beslac-Bumbasirevic, L., Vandelli, L., Lyrer, PA., Nederkoorn, PJ., Tatlisumak, T., & Engelter, ST. (2017). Thrombolysis in Stroke Patients (TRISP) Collaborators. Prognostic significance of proteinuria in stroke patients treated with intravenous thrombolysis. Eur J Neurol, 24 (2). [Cited 2022-08-25].

Gokengin, D., Aho, I., Sarıgül Yıldırım, F., Bukovinova, P., Siwak, E., Papadopoulos, A., Sedlacek, D.,& Kowalska, J. (2019). Exposure to dolutegravir in pregnant women living with HIV in Central and Eastern Europe and neighbouring countries – data from the ECEE Network Group. Ginekol Pol, 90 (7). [Cited 2022-08-25].

Haijanen, J., Sippola, S. Grönroos, J., Rautio, T., Nordström, P., Rantanen, T., Aarnio M., Ilves, I., Hurme, S., Marttila, H., Virtanen, J., Mattila, A., Paajanen H. & Salminen, P. (2018). Optimising the antibiotic treatment of uncomplicated acute appendicitis: a protocol for a multicentre randomised clinical trial (APPAC II trial). On behalf of the APPAC study group. BMC Surgery, 18 (1). [Cited 2022-08-24].

Hecht, I., Dubinsky-Pertzov, B., Karesvuo, P., Achiron, A. & Tuuminen, R. (2020). Association between intraocular lens diopter and posterior capsular opacification. Clinical and Experimental Ophthalmology, 48 (7). [Cited 2022-08-24].

Hecht, I., Karesvuo, P., Achironce, A., Elbazcf, U., Laine, I. & Tuuminen, R. (2020). Antiinflammatory Medication After Cataract Surgery and Posterior Capsular Opacification. American Journal of Ophthalmology, 215. [Cited 2022-08-24].

Holmberg, V., Soini, H., Kivelä, P., Ollgren, J., & Ristola, M. (2019). Epidemiology and outcome of HIV patients in Finland co-infected with tuberculosis 1998-2015. BMC Infectious Diseases, 19, 264. [Cited 2022-08-25].

Ilinca, A., Martinez-Majander, N., Samuelsson, S., Piccinelli, P., Truve, K., Cole, J., Kittner, S., Soller, M., Kristoffersson, U., Tatlisumak, T., Puschmann, A., Putaala, J., & Lindgren, A. (2020). Wholeexome sequencing in 22 young ischemic stroke patients with familial clustering of stroke. Stroke, 51 (4). [Cited 2022-08-25].

Katz, Gregory, editor (2020) Implementing value-based health care in Europe: Handbook for pioneers. EIT Health. [Cited 2022-08-25]

Kauppinen, KJ., Kivelä, P., & Sutinen, J. (2019). Switching from Tenofovir Disoproxil Fumarate to Tenofovir Alafenamide Significantly Worsens the Lipid Profile in a Real-World Setting. AIDS Patient Care and STDS, 33 (12). [Cited 2022-08-25].

Koivisto, S-T., Laaksonen, T., Ahola, J-A., Heleniu, I. & Stenroos, A. (2022). Epidemiology and management of proximal tibia fractures in children and adolescents: a population-based study based on the Kids’ Fracture Tool. Acta Orthopaedica, 93 (826-830). [Cited 2022-10-26].

Kluger, N., Blomqvist, C., & Kivelä, P. (2019). Kaposi sarcoma in Southern Finland (2006-2018). Int J Dermatol, 58 (11). [Cited 2022-08-25].

Lumikari, T.J., Putaala, J., Kerola, A., Sibolt, G., Pirinen, J., Pakarinen, S., Lehto, M., & Nieminen, T., (2019). Continuous 4-week ECG monitoring with adhesive electrodes reveals AF in patients with recent embolic stroke of undetermined source. Annals of Noninvasive Electrocardiology, 24 (5). [Cited 2022-08-25].

Loukovaara, S., Lehtinen, V., Nieminen, R., & Moilanen, J. (2019). Topical levofloxacin, nepafenac and prednisolone acetate medication after cataract surgery in the biggest tertiary eye hospital in Finland during 2015-2018. Acta Ophthalmologica, 97 (6). [Cited 2022-08-25].

Mokka, J., Keemu, H., Koivisto, M., Stormi, T., Vahlberg, T., Virolainen, P., Junnila, M., Seppänen, M., & Mäkelä, K.T. (2013). Experience of structural onlay allografts for the treatment of bone deficiency in revision total hip arthroplasty. Scand J Surg, 102 (4). [Cited 2022-08-25].

Moseholm, E., Fetters, M., Aho, I., Mellgren, A., Johansen, I., Storgaard, M., Pedersen, G., Katzenstein, T., & Weis, N. (2019). Study Protocol: becoming and being a mother living with HIV – a multicentre longitudinal mixed methods study among pregnant women living with HIV, non-pregnant women living with HIV and pregnant women not living with HIV in a high income setting (the 2B MOM study). BMJ Open, 9 (10). [Cited 2022-08-25].

Mäntymäki, H., Mäkelä, K. T., Vahlberg, T., Hirviniemi, J., & Niinimäki, T. (2016). Modular to Monoblock: Difficulties of Detaching the M2a-MagnumTM Head Are Common in Metal-on-metal Revisions. Clinical Orthopaedics and Related Research, 474 (9). [Cited 2022-08-25].

Pihlasviita, S., Mattila, OS., Ritvonen, J., Sibolt, G., Curtze, S., Strbian, D., Harve, H., Pystynen, M., Kuisma, M., Tatlisumak, T., & Lindsberg, PJ. (2018). Diagnosing cerebral ischemia with door-tothrombolysis times below 20 minutes. Neurology, 7 (11). [Cited 2022-08-25].

Polymeris, AA., Curtze, S., Erdur, H., Hametner, C., Heldner, MR., Groot, AE., Zini, A., Béjot, Y., Dietrich, A., Martinez-Majander, N., von Rennenberg, R., Gumbinger, C., Schaedelin, S., De Marchis, GM., Thilemann, S., Traenka, C., Lyrer, PA., Bonati, LH., Wegener, S., Ringleb, PA., Tatlisumak, T., Nolte, CH., Scheitz, JF., Arnold, M., Strbian, D., Nederkoorn, PJ., Gensicke, H., & Engelter, ST; TRISP Collaborators. (2019). Intravenous thrombolysis for suspected ischemic stroke with seizure at onset. Ann Neurol, 86 (5). [Cited 2022-08-25].

Puolanne, A-M., Quadri, S., Vesterinen T., Hiltunen, S., Mustonen A., Kurki, S., Kolho, K-L., Arola, J., & Färkkilä, M. (2022) Can dysplasia surveillance be better targeted in ulcerative colitis by using faecal calprotectin? Scandinavian Journal of Gastroenterology, Epub June 13, 2022. [Cited 2022-08-25].

Putaala, J. (2020). Ischemic Stroke in Young Adults. Cerebrovascular Disease, 26 (2). [Cited 2022-08-25].

Pöyhönen, P., Kuusisto, J., Järvinen, V., Pirinen, J., Räty, H., Lehmonen, Paakkanen, R., Martinez-Majander, N., Putaala, J., & Sinisalo, J. (2020). Left ventricular non-compaction as a potential source for cryptogenic ischemic stroke in the young: A case-control study. PLoS One, 15 (8). [Cited 2022-08-25].

Rajala, S., Järvelä L.S., Huurre, A., Grönroos, M., Rautava, P., & Lähteenmäki, P.M. (2020). Use of electronic patient data storage for evaluating and setting the risk category of late effects in childhood cancer survivors. Pediatric Blood & Cancer, 67 (11). [Cited 2022-08-25]

Ruohoalho, J. (2018). Complications and Their Registration in Otorhinolaryngology – Head and Neck Surgery : Special Emphasis in Tonsil Surgery Quality Registration. University of Helsinki, Faculty of Medicine, Department of Otorhinolaryngology – Head and Neck Surgery. Helsingin yliopisto. [Cited 2022-08-25]

Räty, S., Sallinen, H., Virtanen, P., Haapaniemi, E., Wu, TY., Putaala, J., Meretoja, A., Tatlisumak, Turgut., & Strbian, D. (2021). Occipital intracerebral hemorrhage—clinical characteristics, outcome, and post-ICH epilepsy. Acta Neurologica Scandinavica, 143 (1). [Cited 2022-08-26].

Saarinen, T., Kettunen, U., Pietiläinen, K.H., & Juuti, A. (2018). Is preoperative gastroscopy necessary before sleeve gastrectomy and Roux-en-Y gastric bypass? Surgery for obesity and related diseases, 14. [Cited 2022-08-26].

Scheitz, JF., Gensicke, H., Zinkstok, SM., Curtze, S., Arnold M., Hametner, C., Pezzini, A., Turc, G., Zini, A., Padjen, V., Wegener, S., Nordanstig, A., Kellert, L., Kägi, G., Bejot, Y., Michel, P., Leys, D., Nolte, CH., Nederkoorn, PJ., Engelter, ST; TRISP collaboration. (2018). Cohort profile: Thrombolysis in Ischemic Stroke Patients (TRISP): a multicenter research collaboration. BMJ Open. [Cited 2022-08-26].

Scheitz, JF., Turc, G., Kujala, L., Polymeris, AA., Heldner, MR., Zonneveld, TP., Erdur, H., Curtze, S., Traenka, C., Brenière, C., Wiest, R., Rocco, A., Sibolt, G., Gensicke, H., Endres, M., Martinez-Majander, N., Béjot, Y., Nederkoorn, PJ., Oppenheim, C., Arnold, M., Engelter, ST., Strbian, D., Nolte, CH; TRISP Collaboration. (2017). Intracerebral Hemorrhage and Outcome After Thrombolysis in Stroke Patients Using Selective Serotonin-Reuptake Inhibitors. Stroke, 48 (12). [Cited 2022-08-26].

Seiffge, DJ., Curtze, S., Dequatre-Ponchelle, N., Pezzini, A., Tatlisumak, T., Cordonnier, C., & Werring, D. (2019). Hematoma location and morphology of anticoagulation-associated intracerebral hemorrhage. Neurology, 92 (8). [Cited 2022-08-26].

Sippola, S., Grönroos, J., Sallinen, V., Rautio, T., Nordström, P., Rantanen, T., Hurme, S., Leppäniemi, A., Meriläinen, S., Virtanen, J., & Salminen, P. (2018). A randomised placebocontrolled double-blind multicentre trial comparing antibiotic therapy with placebo in the treatment of uncomplicated acute appendicitis: APPAC III trial study protocol. BMJ Open, 8 (11). [Cited 2022-08-26].

Spaander, FH., Zinkstok, SM., Baharoglu, IM., Gensicke, H., Polymeris, A., Traenka, C., Hametner, C., Ringleb, P., Curtze, S., Martinez-Majander, N., Aarnio, K., Nolte, CH., Scheitz, JF., Leys, D., Hochart, A., Padjen, V., Kägi, G., Pezzini, A., Michel, P., Bill, O., Zini, A., Engelter, ST., Nederkoorn, PJ; Thrombolysis in Ischemic Stroke Patients Collaborators (TrISP). (2017). Sex Differences and Functional Outcome After Intravenous Thrombolysis. Stroke, 48 (3). [Cited 2022-08-26].

Stenroos, A., Kosola, J., Puhakka, J., Laaksonen, T., Ahonen, M. & Nietosvaara, Y. (2019). Routine radiographic follow-up is not necessary after physeal fractures of the distal tibia in children. Acta Orthopedica, 90 (6). [Cited 2022-08-25].

Välimäki, M., Mishina, K., Kaakinen, JK., Holm, SK., Vahlo, J., Kirjonen, M., Pekurinen, V., Tenovuo, O., Korkeila, J, Hämäläinen, H., Sarajuuri, J., Rantanen, P., Orenius, T., & Koponen, A. (2018). Digital Gaming for Improving the Functioning of People With Traumatic Brain Injury: Randomized Clinical Feasibility Study. J Med Internet Res, 20 (3). [Cited 2022-08-26].

Zonneveld, TP., Curtze, S., Zinkstok, SM., Gensicke, H., Moulin, S., Scheitz, JF., Seiffge, DJ., Hametner, C., Heldner, MR., Traenka, C., Erdur, H., Baharoglu, I., Martinez-Majander, N., Pezzini, A., Zini, A., Padjen, V., Correia, PN., Strbian, D., Michel, P., Béjot, Y., Arnold, M., Leys, D., Ringleb, PA., Tatlisumak, T., Nolte, CH., Engelter, ST., Nederkoorn, PJ; TRISP collaborators. (2018). Non-office-hours admission affects intravenous thrombolysis treatment times and clinical outcome. J Neurol Neurosurg Psychiatry, 89 (9). [Cited 2022-08-26].